Loading...
The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I
BACKGROUND: Escherichia coli DNA topoisomerase I binds three Zn(II) with three tetracysteine motifs which, together with the 14 kDa C-terminal region, form a 30 kDa DNA binding domain (ZD domain). The 67 kDa N-terminal domain (Top67) has the active site tyrosine for DNA cleavage but cannot relax neg...
Na minha lista:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2002
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC115839/ https://ncbi.nlm.nih.gov/pubmed/12052259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-3-13 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|