Decrease in hepatic cytochrome P-450 by cobalt. Evidence for a role of cobalt protoporphyrin.

Exposure of cultured chick-embryo hepatocytes to increasing concentrations of CoCl2 in the presence of allylisopropylacetamide results in formation of cobalt protoporphyrin, with a reciprocal decrease in haem and cytochrome P-450. Treatment of rats with CoCl2 (84 mumol/kg) and 5-aminolaevulinate (0....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sinclair, J F, Sinclair, P R, Healey, J F, Smith, E L, Bonkowsky, H L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1982
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158321/
https://ncbi.nlm.nih.gov/pubmed/7115319
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