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A T-stem slip in human mitochondrial tRNA(Leu)(CUN) governs its charging capacity

The human mitochondrial tRNA(Leu)(CUN) [hmtRNA(Leu)(CUN)] corresponds to the most abundant codon for leucine in human mitochondrial protein genes. Here, in vitro studies reveal that the U48C substitution in hmtRNA(Leu)(CUN), which corresponds to the pathological T12311C gene mutation, improved the a...

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Bibliografiske detaljer
Main Authors: Hao, Rui, Zhao, Ming-Wei, Hao, Zhan-Xi, Yao, Yong-Neng, Wang, En-Duo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157101/
https://ncbi.nlm.nih.gov/pubmed/15972857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki677
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