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Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: A potential component of nociception
A crucial biochemical reaction in vertebrates is progesterone conversion into neuroactive metabolites such as dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (3α,5α-THP), which regulate several neurobiological processes, including stress, depression, neuroprotection, and analgesia. 3α,5α-THP...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1157043/ https://ncbi.nlm.nih.gov/pubmed/15951421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502968102 |
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