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Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: A potential component of nociception

A crucial biochemical reaction in vertebrates is progesterone conversion into neuroactive metabolites such as dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (3α,5α-THP), which regulate several neurobiological processes, including stress, depression, neuroprotection, and analgesia. 3α,5α-THP...

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Detalhes bibliográficos
Main Authors: Patte-Mensah, Christine, Kibaly, Cherkaouia, Mensah-Nyagan, Ayikoe G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157043/
https://ncbi.nlm.nih.gov/pubmed/15951421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502968102
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