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Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread

The US3 protein is a viral kinase that is conserved among the Alphaherpesvirinae. Here, we show that US3 of the swine alphaherpesvirus pseudorabies virus causes dramatic alterations in the cytoskeleton, resulting in the formation of long actin- and microtubule-containing cell projections in infected...

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Библиографические подробности
Главные авторы: Favoreel, Herman W., Van Minnebruggen, Geert, Adriaensen, Dirk, Nauwynck, Hans J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157013/
https://ncbi.nlm.nih.gov/pubmed/15951429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409099102
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