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Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread

The US3 protein is a viral kinase that is conserved among the Alphaherpesvirinae. Here, we show that US3 of the swine alphaherpesvirus pseudorabies virus causes dramatic alterations in the cytoskeleton, resulting in the formation of long actin- and microtubule-containing cell projections in infected...

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Detalhes bibliográficos
Main Authors: Favoreel, Herman W., Van Minnebruggen, Geert, Adriaensen, Dirk, Nauwynck, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1157013/
https://ncbi.nlm.nih.gov/pubmed/15951429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409099102
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