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Antiviral activity of the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine.

3'-NH2-BV-dUrd, the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine, was found to be a potent and selective inhibitor of herpes simplex virus type 1 (HSV-1) and varicella-zoster virus (VZV) replication. 3'-NH2-BV-dUrd was about 4-12 times less potent but equally selec...

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Main Authors: De Clercq, E, Descamps, J, Balzarini, J, Fukui, T, Allaudeen, H S
格式: Artigo
語言:Inglês
出版: 1983
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1154377/
https://ncbi.nlm.nih.gov/pubmed/6307280
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