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The role of 5-aminolaevulinate synthase, haem oxygenase and ligand formation in the mechanism of maintenance of cytochrome P-450 concentration in hepatocyte culture.

The present work shows that the ability of pyridines e.g. metyrapone, to maintain the cytochrome P-450 concentration in cultured hepatocytes is not due to their ability to alter the 5-aminolaevulinate synthase and haem oxygenase activities of the hepatocytes. Since ligands such as metyrapone will pr...

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Hlavní autoři: Hockin, L J, Paine, A J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1154299/
https://ncbi.nlm.nih.gov/pubmed/6688177
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