Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem.

To examine current models for the co-ordinate regulation of 5-aminolaevulinate (ALA) synthase and cytochrome P-450 we have determined the effect of drugs, inhibitors of haem biosynthesis, haem and cycloheximide on the steady-state expression of mRNAs for ALA synthase and a phenobarbital-inducible cy...

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Detalhes bibliográficos
Main Authors: Hamilton, J W, Bement, W J, Sinclair, P R, Sinclair, J F, Wetterhahn, K E
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135219/
https://ncbi.nlm.nih.gov/pubmed/3196319
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