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Active-site-directed inactivators of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of Streptomyces albus G.

Several types of active-site-directed inactivators (inhibitors) of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase were tested. (i) Among the heavy-atom-containing compounds examined, K2Pt(C2O4)2 inactivates the enzyme with a second-order rate constant of about 6 X 10(-2)M-1 X S-1 a...

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Bibliographic Details
Main Authors: Charlier, P, Dideberg, O, Jamoulle, J C, Frère, J M, Ghuysen, J M, Dive, G, Lamotte-Brasseur, J
Format: Artigo
Language:Inglês
Published: 1984
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153542/
https://ncbi.nlm.nih.gov/pubmed/6743245
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