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Regulation of activity of purified guanylate cyclase from liver that is unresponsive to nitric oxide.

Guanylate cyclase was purified from rat liver supernatant. Electrophoresis under denaturing conditions revealed one major peptide of Mr approx. 69 000. On the basis of the Stokes radius (4.7 nm) and S20,w (6.4S), the calculated Mr value of the native enzyme was 133 000, i.e. it is apparently a homod...

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Detalhes bibliográficos
Main Authors: Tsai, S C, Adamik, R, Manganiello, V C, Vaughan, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152422/
https://ncbi.nlm.nih.gov/pubmed/6140917
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