Sialylation of Group B Streptococcal Capsular Polysaccharide Is Mediated by cpsK and Is Required for Optimal Capsule Polymerization and Expression

Several bacterial pathogens have evolved the means to escape immune detection by mimicking host cell surface carbohydrates that are crucial for self/non-self recognition. Sialic acid, a terminal residue on these carbohydrates, inhibits activation of the alternate pathway of complement by recruiting...

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Main Authors: Chaffin, D. O., Mentele, L. M., Rubens, C. E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Molecular Biology of Pathogens
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151781/
https://ncbi.nlm.nih.gov/pubmed/15968073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.13.4615-4626.2005
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