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Identification of Streptococcus pneumoniae Cps2C Residues That Affect Capsular Polysaccharide Polymerization, Cell Wall Ligation, and Cps2D Phosphorylation

A number of single amino acid substitutions throughout Streptococcus pneumoniae Cps2C were found to affect its function and confer either a mucoid or a small colony phenotype. These mutants exhibit significant changes in capsular polysaccharide (CPS) profile relative to that of wild-type pneumococci...

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Main Authors: Byrne, James P., Morona, Judy K., Paton, James C., Morona, Renato
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133057/
https://ncbi.nlm.nih.gov/pubmed/21378192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00074-11
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