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Deletion of a single hydrogen bonding atom from the MS2 RNA operator leads to dramatic rearrangements at the RNA–coat protein interface

The MS2 coat protein binds specifically to an RNA hairpin formed within the viral genome. By soaking different RNA fragments into crystals of MS2 coat protein capsids it is possible to determine the X-ray structure of the RNA–protein complexes formed. Here we present the structure to 2.85 Å resoluti...

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Detalhes bibliográficos
Main Authors: Grahn, Elin, Stonehouse, Nicola J., Adams, Chris J., Fridborg, Kerstin, Beigelman, Leonid, Matulic-Adamic, Jasenka, Warriner, Stuart L., Stockley, Peter G., Liljas, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115176/
https://ncbi.nlm.nih.gov/pubmed/11095669
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