Cisplatin–DNA adducts inhibit translocation of the Ku subunits of DNA-PK
We have determined the effect of cisplatin–DNA damage on the ability of the DNA-dependent protein kinase (DNA-PK) to interact with duplex DNA molecules in vitro. The Ku DNA binding subunits of DNA-PK display a reduced ability to translocate on duplex DNA containing cisplatin–DNA adducts compared to...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11095672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.23.4634 |
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