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Cisplatin–DNA adducts inhibit translocation of the Ku subunits of DNA-PK

We have determined the effect of cisplatin–DNA damage on the ability of the DNA-dependent protein kinase (DNA-PK) to interact with duplex DNA molecules in vitro. The Ku DNA binding subunits of DNA-PK display a reduced ability to translocate on duplex DNA containing cisplatin–DNA adducts compared to...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Turchi, John J., Henkels, Karen M., Zhou, Yun
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115169/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11095672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.23.4634
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