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CREB-Binding Protein and Histone Deacetylase Regulate the Transcriptional Activity of Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50

Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) open reading frame 50 (ORF50) encodes a viral transcriptional activator, which binds to the KSHV promoter and stimulates the transcription of viral early and late genes, thus activating the lytic cycle of KSHV. We report here that KSHV ORF50 b...

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Autors principals: Gwack, Yousang, Byun, Hyewon, Hwang, Seungmin, Lim, Chunghun, Choe, Joonho
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC115137/
https://ncbi.nlm.nih.gov/pubmed/11160690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1909-1917.2001
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