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Jaagsiekte Sheep Retrovirus Env Protein Stabilizes Retrovirus Vectors against Inactivation by Lung Surfactant, Centrifugation, and Freeze-Thaw Cycling

Jaagsiekte sheep retrovirus (JSRV) replicates in the lungs of sheep and causes the secretion of copious lung fluid containing the virus. Adaptation of JSRV to infection and replication in the lung and its apparent resistance to the denaturing activity of lung fluid suggest that vectors based on JSRV...

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Autors principals: Coil, David A., Strickler, John H., Rai, Sharath K., Miller, A. Dusty
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC115133/
https://ncbi.nlm.nih.gov/pubmed/11507233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8864-8867.2001
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