Jaagsiekte Sheep Retrovirus Env Protein Stabilizes Retrovirus Vectors against Inactivation by Lung Surfactant, Centrifugation, and Freeze-Thaw Cycling

Jaagsiekte sheep retrovirus (JSRV) replicates in the lungs of sheep and causes the secretion of copious lung fluid containing the virus. Adaptation of JSRV to infection and replication in the lung and its apparent resistance to the denaturing activity of lung fluid suggest that vectors based on JSRV...

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Detalhes bibliográficos
Principais autores: Coil, David A., Strickler, John H., Rai, Sharath K., Miller, A. Dusty
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115133/
https://ncbi.nlm.nih.gov/pubmed/11507233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8864-8867.2001
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