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Deletion of two growth-factor repeats from the low-density-lipoprotein receptor accelerates its degradation.

The region of the low-density-lipoprotein (LDL) receptor showing sequence similarity to the epidermal-growth-factor (EGF) precursor is required for LDL binding and the acid-induced dissociation of ligand and receptor. We describe here a naturally occurring mutant LDL receptor, found in a patient wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van der Westhuyzen, D R, Stein, M L, Henderson, H E, Marais, A D, Fourie, A M, Coetzee, G A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151296/
https://ncbi.nlm.nih.gov/pubmed/1872803
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