Deletion of two growth-factor repeats from the low-density-lipoprotein receptor accelerates its degradation.

Ítems similars

• Deletion in the first cysteine-rich repeat of low density lipoprotein receptor impairs its transport but not lipoprotein binding in fibroblasts from a subject with familial hypercholesterolemia.
  per: Leitersdorf, E, et al.
  Publicat: (1988)
• Two mutant low-density-lipoprotein receptors in Afrikaners slowly processed to surface forms exhibiting rapid degradation or functional heterogeneity.
  per: Fourie, A M, et al.
  Publicat: (1988)
• Low-density-lipoprotein receptors in human fibroblasts are not degraded in lysosomes.
  per: Casciola, L A, et al.
  Publicat: (1989)
• Neutrophil association and degradation of normal and acute-phase high-density lipoprotein 3.
  per: Shephard, E G, et al.
  Publicat: (1987)
• Two common low density lipoprotein receptor gene mutations cause familial hypercholesterolemia in Afrikaners.
  per: Leitersdorf, E, et al.
  Publicat: (1989)