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Comparison of the activity and conformation changes of lactate dehydrogenase H4 during denaturation by guanidinium chloride.

The inactivation and unfolding of lactate dehydrogenase (LDH) during denaturation by guanidinium chloride (GuHCl) under diverse conditions have been compared. Unfolding of the native conformation, as monitored by fluorescence and c.d. measurements, occurs in two stages with increasing GuHCl concentr...

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Detalhes bibliográficos
Main Authors: Ma, Y Z, Tsou, C L
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151211/
https://ncbi.nlm.nih.gov/pubmed/1854334
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