Genetic Control of Neuroadapted Sindbis Virus Replication in Female Mice Maps to Chromosome 2 and Associates with Paralysis and Mortality

Neuroadapted Sindbis virus (NSV) infection of mice causes hindlimb paralysis and 100% mortality in the C57BL/6 mouse strain, while adults of the BALB/cBy mouse strain are resistant to fatal encephalomyelitis. Levels of viral RNA are higher in the brains of infected C57BL/6 mice than in BALB/cBy mice...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Thach, Dzung C., Kleeberger, Steven R., Tucker, Pamela C., Griffin, Diane E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11507212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.18.8674-8680.2001
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