Genetic Control of Neuroadapted Sindbis Virus Replication in Female Mice Maps to Chromosome 2 and Associates with Paralysis and Mortality

Neuroadapted Sindbis virus (NSV) infection of mice causes hindlimb paralysis and 100% mortality in the C57BL/6 mouse strain, while adults of the BALB/cBy mouse strain are resistant to fatal encephalomyelitis. Levels of viral RNA are higher in the brains of infected C57BL/6 mice than in BALB/cBy mice...

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Bibliographische Detailangaben
Hauptverfasser: Thach, Dzung C., Kleeberger, Steven R., Tucker, Pamela C., Griffin, Diane E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC115112/
https://ncbi.nlm.nih.gov/pubmed/11507212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8674-8680.2001
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