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An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production

Phospholipase C and several inositol polyphosphate kinase (IPK) activities generate a branched ensemble of inositol polyphosphate second messengers that regulate cellular signaling pathways in the nucleus and cytoplasm. Here, we report that mice deficient for Ipk2 (also known as inositol polyphospha...

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Autori principali: Frederick, Joshua P., Mattiske, Deidre, Wofford, Jessica A., Megosh, Louis C., Drake, Li Yin, Chiou, Shean-Tai, Hogan, Brigid L. M., York, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150869/
https://ncbi.nlm.nih.gov/pubmed/15939867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503706102
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