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Linear-After-The-Exponential (LATE)-PCR: Primer design criteria for high yields of specific single-stranded DNA and improved real-time detection

Traditional asymmetric PCR uses conventional PCR primers at unequal concentrations to generate single-stranded DNA. This method, however, is difficult to optimize, often inefficient, and tends to promote nonspecific amplification. An alternative approach, Linear-After-The-Exponential (LATE)-PCR, sol...

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Podrobná bibliografie
Hlavní autoři: Pierce, Kenneth E., Sanchez, J. Aquiles, Rice, John E., Wangh, Lawrence J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150831/
https://ncbi.nlm.nih.gov/pubmed/15937116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501946102
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