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Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes
Trypanosoma brucei is a protozoan parasite that causes African sleeping sickness. T. brucei multiplies extracellularly in the bloodstream, relying on antigenic variation of a dense variant surface glycoprotein (VSG) coat to escape antibody-mediated lysis. We investigated the role of VSG in prolifera...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150830/ https://ncbi.nlm.nih.gov/pubmed/15937117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501886102 |
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