Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC

CD1 molecules play an important role in the immune system, presenting lipid-containing antigens to T and NKT cells. CD1 genes have long been thought to be as ancient as MHC class I and II genes, based on various arguments, but thus far they have been described only in mammals. Here we describe two C...

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Detalhes bibliográficos
Main Authors: Salomonsen, Jan, Sørensen, Maria Rathmann, Marston, Denise A., Rogers, Sally L., Collen, Trevor, van Hateren, Andrew, Smith, Adrian L., Beal, Richard K., Skjødt, Karsten, Kaufman, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150808/
https://ncbi.nlm.nih.gov/pubmed/15939887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409213102
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