Antibody Protects Macaques against Vaginal Challenge with a Pathogenic R5 Simian/Human Immunodeficiency Virus at Serum Levels Giving Complete Neutralization In Vitro

A major unknown in human immunodeficiency virus (HIV-1) vaccine design is the efficacy of antibodies in preventing mucosal transmission of R5 viruses. These viruses, which use CCR5 as a coreceptor, appear to have a selective advantage in transmission of HIV-1 in humans. Hence R5 viruses predominate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Parren, Paul W. H. I., Marx, Preston A., Hessell, Ann J., Luckay, Amara, Harouse, Janet, Cheng-Mayer, Cecilia, Moore, John P., Burton, Dennis R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2001
विषय:
Pathogenesis and Immunity
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC115078/
https://ncbi.nlm.nih.gov/pubmed/11483779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.8340-8347.2001
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