Inhibition of Human Immunodeficiency Virus Type 1 Rev Function by a Dominant-Negative Mutant of Sam68 through Sequestration of Unspliced RNA at Perinuclear Bundles

Human immunodeficiency virus (HIV) type 1 encodes an essential protein, Rev, which functions to transport unspliced and singly spliced viral transcripts from the nucleus to the cytoplasm to allow expression of the viral structural proteins. It has previously been reported that Sam68 synergistically...

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Bibliographic Details
Main Authors: Soros, Vanessa B., Carvajal, Héctor Valderrama, Richard, Stéphane, Cochrane, Alan W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC115065/
https://ncbi.nlm.nih.gov/pubmed/11483766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.8203-8215.2001
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