Human Immunodeficiency Virus Type 1 DNA Sequences Genetically Damaged by Hypermutation Are Often Abundant in Patient Peripheral Blood Mononuclear Cells and May Be Generated during Near-Simultaneous Infection and Activation of CD4(+) T Cells

G-to-A hypermutation has been sporadically observed in human immunodeficiency virus type 1 (HIV-1) proviral sequences from patient peripheral blood mononuclear cells (PBMC) and virus cultures but has not been systematically evaluated. PCR primers matched to normal and hypermutated sequences were use...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Janini, Mario, Rogers, Melissa, Birx, Deborah R., McCutchan, Francine E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Recombination and Evolution
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.17.7973-7986.2001
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