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Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory

The evidence for the reverse transcriptase mechanism of somatic hypermutation is substantial and multifactorial. In this 60th anniversary year of the publication of Sir MacFarlane Burnet’s Clonal Selection Theory, the evidence is briefly reviewed and updated.

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Autor principal: Edward J. Steele
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017-11-01
Col·lecció:Frontiers in Immunology
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Accés en línia:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01611/full
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