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Mutations in the Fusion Peptide and Adjacent Heptad Repeat Inhibit Folding or Activity of the Newcastle Disease Virus Fusion Protein

Paramyxovirus fusion proteins have two heptad repeat domains, HR1 and HR2, which have been implicated in the fusion activity of the protein. Peptides with sequences from these two domains form a six-stranded coiled coil, with the HR1 sequences forming a central trimer (K. A. Baker, R. E. Dutch, R. A...

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書目詳細資料
發表在:J Virol
Principais autores: Sergel, Theresa A., McGinnes, Lori W., Morrison, Trudy G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2001
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115037/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.17.7934-7943.2001
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