Mutations in the Fusion Peptide and Adjacent Heptad Repeat Inhibit Folding or Activity of the Newcastle Disease Virus Fusion Protein

Paramyxovirus fusion proteins have two heptad repeat domains, HR1 and HR2, which have been implicated in the fusion activity of the protein. Peptides with sequences from these two domains form a six-stranded coiled coil, with the HR1 sequences forming a central trimer (K. A. Baker, R. E. Dutch, R. A...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sergel, Theresa A., McGinnes, Lori W., Morrison, Trudy G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.17.7934-7943.2001
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