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Transplantation of spermatogonial stem cells isolated from leukemic mice restores fertility without inducing leukemia
More than 70% of patients survive childhood leukemia, but chemotherapy and radiation therapy cause irreversible impairment of spermatogenesis. Although autotransplantation of germ cells holds promise for restoring fertility, contamination by leukemic cells may induce relapse. In this study, we isola...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150287/ https://ncbi.nlm.nih.gov/pubmed/15965502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24189 |
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