Transplantation of spermatogonial stem cells isolated from leukemic mice restores fertility without inducing leukemia

More than 70% of patients survive childhood leukemia, but chemotherapy and radiation therapy cause irreversible impairment of spermatogenesis. Although autotransplantation of germ cells holds promise for restoring fertility, contamination by leukemic cells may induce relapse. In this study, we isola...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fujita, Kazutoshi, Ohta, Hiroshi, Tsujimura, Akira, Takao, Tetsuya, Miyagawa, Yasushi, Takada, Shingo, Matsumiya, Kiyomi, Wakayama, Teruhiko, Okuyama, Akihiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2005
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150287/
https://ncbi.nlm.nih.gov/pubmed/15965502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24189
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