Different Levels of T-Cell Receptor Triggering Induce Distinct Functions in Hepatitis B and Hepatitis C Virus-Specific Human CD4(+) T-Cell Clones

CD4(+) T cells play a major role in the host defense against viruses and intracellular microbes. During the natural course of such an infection, specific CD4(+) T cells are exposed to a wide range of antigen concentrations depending on the body compartment and the stage of disease. While epitope var...

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Detalhes bibliográficos
Main Authors: Diepolder, Helmut M., Gruener, Norbert H., Gerlach, J. Tilman, Jung, Maria-Christina, Wierenga, Eddy A., Pape, Gerd R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115022/
https://ncbi.nlm.nih.gov/pubmed/11483723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.7803-7810.2001
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