Use of Patient-Derived Human Immunodeficiency Virus Type 1 Integrases To Identify a Protein Residue That Affects Target Site Selection

To identify parts of retroviral integrase that interact with cellular DNA, we tested patient-derived human immunodeficiency virus type 1 (HIV-1) integrases for alterations in the choice of nonviral target DNA sites. This strategy took advantage of the genetic diversity of HIV-1, which provided 75 in...

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Bibliografiset tiedot
Päätekijät: Harper, Amy L., Skinner, Lynn M., Sudol, Malgorzata, Katzman, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC115014/
https://ncbi.nlm.nih.gov/pubmed/11462051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7756-7762.2001
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