Use of Patient-Derived Human Immunodeficiency Virus Type 1 Integrases To Identify a Protein Residue That Affects Target Site Selection

To identify parts of retroviral integrase that interact with cellular DNA, we tested patient-derived human immunodeficiency virus type 1 (HIV-1) integrases for alterations in the choice of nonviral target DNA sites. This strategy took advantage of the genetic diversity of HIV-1, which provided 75 in...

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Publié dans:	J Virol
Auteurs principaux:	Harper, Amy L., Skinner, Lynn M., Sudol, Malgorzata, Katzman, Michael
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Replication
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7756-7762.2001
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