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Enhancement of Muscle Gene Delivery with Pseudotyped Adeno-Associated Virus Type 5 Correlates with Myoblast Differentiation

Adeno-associated virus (AAV)-based muscle gene therapy has achieved tremendous success in numerous animal models of human diseases. Recent clinical trials with this vector have also demonstrated great promise. However, to achieve therapeutic benefit in patients, large inocula of virus will likely be...

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Autors principals: Duan, Dongsheng, Yan, Ziying, Yue, Yongping, Ding, Wei, Engelhardt, John F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC115001/
https://ncbi.nlm.nih.gov/pubmed/11462038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7662-7671.2001
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