Requirement for Uracil-DNA Glycosylase during the Transition to Late-Phase Cytomegalovirus DNA Replication

Cytomegalovirus gene UL114, a homolog of mammalian uracil-DNA glycosylase (UNG), is required for efficient viral DNA replication. In quiescent fibroblasts, UNG mutant virus replication is delayed for 48 h and follows the virus-induced expression of cellular UNG. In contrast, mutant virus replication...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Courcelle, Charmain Tan, Courcelle, Justin, Prichard, Mark N., Mocarski, Edward S.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Replication
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462031/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7592-7601.2001
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