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E1B 19K Blocks Bax Oligomerization and Tumor Necrosis Factor Alpha-Mediated Apoptosis
Tumor necrosis factor alpha (TNF-α)-mediated death signaling causes the recruitment of monomeric pro- apoptotic Bax into a 500-kDa protein complex. The adenovirus Bcl-2 homologue, E1B 19K, inhibits TNF-α-mediated apoptosis, interacts with Bax, and blocked the formation of the 500-kDa Bax complex. TN...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114986/ https://ncbi.nlm.nih.gov/pubmed/11462023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7506-7516.2001 |
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