Recombinant human interferon-gamma. Differences in glycosylation and proteolytic processing lead to heterogeneity in batch culture.

Recombinant human interferon-gamma (Hu-IFN-gamma) produced by Chinese-hamster ovary (CHO) cells was analysed by immunoprecipitation and SDS/PAGE. Up to twelve molecular-mass variants were secreted by this cell line. Three variants were recovered after enzymic removal of all N-linked oligosaccharides...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Curling, E M, Hayter, P M, Baines, A J, Bull, A T, Gull, K, Strange, P G, Jenkins, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149704/
https://ncbi.nlm.nih.gov/pubmed/2125204
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi