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Stability of the Human Papillomavirus Type 18 E2 Protein Is Regulated by a Proteasome Degradation Pathway through Its Amino-Terminal Transactivation Domain

The E2 proteins of papillomaviruses regulate both viral transcription and DNA replication. The human papillomavirus type 18 (HPV18) E2 protein has been shown to repress transcription of the oncogenic E6 and E7 genes, inducing growth arrest in HeLa cells. Using HPV18 E2 fused to the green fluorescent...

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Библиографические подробности
Главные авторы: Bellanger, Sophie, Demeret, Caroline, Goyat, Sylvain, Thierry, Françoise
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC114960/
https://ncbi.nlm.nih.gov/pubmed/11461997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7244-7251.2001
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