Stability of the Human Papillomavirus Type 18 E2 Protein Is Regulated by a Proteasome Degradation Pathway through Its Amino-Terminal Transactivation Domain

The E2 proteins of papillomaviruses regulate both viral transcription and DNA replication. The human papillomavirus type 18 (HPV18) E2 protein has been shown to repress transcription of the oncogenic E6 and E7 genes, inducing growth arrest in HeLa cells. Using HPV18 E2 fused to the green fluorescent...

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Bibliographic Details
Main Authors: Bellanger, Sophie, Demeret, Caroline, Goyat, Sylvain, Thierry, Françoise
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114960/
https://ncbi.nlm.nih.gov/pubmed/11461997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7244-7251.2001
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