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Effects of threshold choice on biological conclusions reached during analysis of gene expression by DNA microarrays

Global analysis of gene expression by using DNA microarrays is employed increasingly to search for differences in biological properties between normal and diseased tissue. In such studies, expression that deviates from defined thresholds commonly is used for creating genetic signatures that characte...

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Detalhes bibliográficos
Main Authors: Pan, Kuang-Hung, Lih, Chih-Jian, Cohen, Stanley N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149502/
https://ncbi.nlm.nih.gov/pubmed/15951424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502674102
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