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Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines

Reverse genetics was used to analyze the host range of two avian influenza viruses which differ in their ability to replicate in mouse and human cells in culture. Engineered viruses carrying sequences encoding amino acids 362 to 581 of PB2 from a host range variant productively infect mouse and huma...

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Main Authors: Yao, Yongxiu, Mingay, Louise J., McCauley, John W., Barclay, Wendy S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC114950/
https://ncbi.nlm.nih.gov/pubmed/11333926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5410-5415.2001
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