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Residue 627 of PB2 Is a Determinant of Cold Sensitivity in RNA Replication of Avian Influenza Viruses

Human influenza A viruses replicate in the upper respiratory tract at a temperature of about 33°C, whereas avian viruses replicate in the intestinal tract at a temperature close to 41°C. In the present study, we analyzed the influence of low temperature (33°C) on RNA replication of avian and human v...

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Udgivet i:J Virol
Principais autores: Massin, Pascale, van der Werf, Sylvie, Naffakh, Nadia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114948/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11333924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.11.5398-5404.2001
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