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Residue 627 of PB2 Is a Determinant of Cold Sensitivity in RNA Replication of Avian Influenza Viruses

Human influenza A viruses replicate in the upper respiratory tract at a temperature of about 33°C, whereas avian viruses replicate in the intestinal tract at a temperature close to 41°C. In the present study, we analyzed the influence of low temperature (33°C) on RNA replication of avian and human v...

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Detalhes bibliográficos
Main Authors: Massin, Pascale, van der Werf, Sylvie, Naffakh, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114948/
https://ncbi.nlm.nih.gov/pubmed/11333924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5398-5404.2001
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