Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice

The association between circulating concentrations of C-reactive protein (CRP) and future atherothrombotic events has provoked speculation about a possible pathogenetic role of CRP. However, we show here that transgenic expression of human CRP had no effect on development, progression, or severity o...

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Bibliografiske detaljer
Main Authors: Hirschfield, Gideon M., Gallimore, J. Ruth, Kahan, Melvyn C., Hutchinson, Winston L., Sabin, Caroline A., Benson, G. Martin, Dhillon, Amar P., Tennent, Glenys A., Pepys, Mark B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149444/
https://ncbi.nlm.nih.gov/pubmed/15919817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503202102
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