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Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations

Timothy syndrome (TS) is a multisystem disorder that causes syncope and sudden death from cardiac arrhythmias. Prominent features include congenital heart disease, immune deficiency, intermittent hypoglycemia, cognitive abnormalities, and autism. All TS individuals have syndactyly (webbing of finger...

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Detalhes bibliográficos
Main Authors: Splawski, Igor, Timothy, Katherine W., Decher, Niels, Kumar, Pradeep, Sachse, Frank B., Beggs, Alan H., Sanguinetti, Michael C., Keating, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149428/
https://ncbi.nlm.nih.gov/pubmed/15863612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502506102
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