In Vivo Selection of a Lymphocytic Choriomeningitis Virus Variant That Affects Recognition of the GP33-43 Epitope by H-2D(b) but Not H-2K(b)

CD8 T cells drive the protective immune response to lymphocytic choriomeningitis virus (LCMV) infection and are thus a determining force in the selection of viral variants. To examine how escape mutations affect the presentation and recognition of overlapping T-cell epitopes, we isolated an LCMV var...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Puglielli, Maryann T., Zajac, Allan J., van der Most, Robbert G., Dzuris, John L., Sette, Alessandro, Altman, John D., Ahmed, Rafi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11333891/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.11.5099-5107.2001
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